Skip to main content
. 2023 Jan 18;17:100219. doi: 10.1016/j.clinpr.2023.100219

Table 1.

Clinical and pathology findings of the three fetal demise cases in pregnancies with confirmed SARS-CoV-2 infection.

Case number and notification date (DD/MM/YYYY) Fetal sex and GA at pregnancy termination (weeks, days) Fetal anthropometry* (Weight, g); (Height, cm); (HC, cm) Macroscopic findings Microscopic findings Case conclusion
1
(01/08/2020)
Female; 36 2/7 2205 (z-score: 0.17); 47 (z-score: −1.26); 32.5 (z-score: 0.18) -Macerated body, with sloughing of more than 50% of the total body surface
-Overlapping head sutures due to softening of the encephalic structures.
-Generalized visceral congestion with serohematic fluid in pleural, pericardial, and peritoneal cavities.
-External petechiae and congestive appearance in both lungs.
-Hepatic subcapsular hematoma.
-Pulmonary lytic changes, interstitial edema, and alveolar hemorrhage.
-Presence of interstitial hemorrhagic foci in the heart.
Intrauterine death greater than 48 h with signs of hypoxic-ischemic injury.
2
(14/06/2021)
Female; 25 2/7 700 (z-score: −0.10); NA; NA -Positional deformity of upper and lower limbs with bilateral dorsiflexion of the feet and hands, and external rotation of the hip. –Thoracic, pericardial, and peritoneal cavities with abundant hemorrhagic effusion. -Heart: no inflammatory process. -Lung: tubular development phase, consistent with the second trimester, without inflammatory process or morphological alteration in development. Symmetric intrauterine growth restriction and possible fetal pulmonary hypertension.
3
(30/06/2021)
Female 37 1/7 2630 (z-score: −0.53); 47 (z-score: −0.24) Loose nuchal cord. Discrete skin sphacelation. NA NA

Abbreviations: GA: gestational age, g: grams, cm: centimeters, NA: Not available.

*Fetal anthropometric features were calculated via Intergrwoth-21st newborn growth standards, accounting for sex and gestational age.