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. 2023 Jan 6;11(1):65–72. doi: 10.12998/wjcc.v11.i1.65

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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Schematic view of gut microbiota, short chain fatty acids and type 2 diabetes mellitus. GLP 1: Glucagon like peptide 1; GPCR41: G-protein-coupled receptor 41; GPCR43: G-protein-coupled receptor 43; IR: Insulin resistance; PYY: Peptide tyrosine-tyrosine; SCFA: Short chain fatty acid; T2DM: Type 2 diabetes mellitus.