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. 2023 Jan 17;25:5. doi: 10.1186/s13058-023-01602-x

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Stratified analyses of breast cancer associations. Associations of the metabolites associated with breast cancer at FDR < 0.20 grouped in correlated blocks (A) in pre- and postmenopausal women, and (B) in women with ER+ or ER− breast cancer. Associations marked with † differed significantly (p < 0.05) between the two groups. An * next to a metabolite name indicates a level two (putative annotation) compound identification, whereas level one (definitive) identification requires comparing two or more properties of the metabolite, such as retention time, m/z, or fragmentation mass spectrum, to those for an authentic chemical standard, level two (putative) identification requires comparison of only one of these properties