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Mapping of Class B corticotropin-releasing factor receptor. A. Results of mapping the Class A C-X-C motif chemokine receptor 4, CXCR1 (PDB ID 3OE9) (blue), shown as a yellow mesh. The allosteric ligand 1QW (green) from Class B corticotropin-releasing factor receptor 1, CRFR1 (PDB ID 4K5Y) is shown for reference. B. Conserved residues (gray) of 4K5Y that are part of the 1QW binding site.
