Figure 2.

In control and mineralocorticoid receptor (MR) knockout (KO) mice, the percentage of MR-positive cells in the connecting tubule (CNT)/cortical collecting duct (CCD) is similar to that in the late distal convoluted tubule (DCT2)/CNT. A and B: percentage of MR-positive cells in the CNT/CCD (left) and DCT2/CNT (right) from control (A) and MR KO mice (B). Each point represents the analysis of a corresponding segment from an individual isolated tubule. The same immunohistochemical preparations were used as in Fig. 1, but the CNT/CCD and DCT2/CNT regions were analyzed separately. To indicate the origin of each tubular segment, the dots are color coded using the same colors as used for the individual mice in Fig. 1. Data are presented as medians and quartiles.