TABLE 3.
Histopathology in B. burgdorferi-infected rabbit skin following i.d. infection of naive rabbits
| Cell type | Immunohistochemical staining at (h p.i.)a:
|
||||||
|---|---|---|---|---|---|---|---|
| 2 (9/9) | 12 (9/9) | 24 (9/9) | 36 (9/9) | 48 (9/9) | 72 (9/9) | 96 (9/9) | |
| B. burgdorferi | + | + | + | + | + | + | + |
| B lymphocytes | − | − | − | − | − | − | − |
| T lymphocytes | − | − | − | − | − | − | − |
| CD11b+ cells | +b | ++b | ++b | +b | +b | +/−c | +/−c |
a
The number of skin-culture-positive rabbits per total number of animals observed is indicated in parentheses. Observations made for six rabbits: −, none; +/−, few/some; +, moderate; ++, numerous.
b
PMNs as determined by microscopic analysis of H&E-stained serial sections.
c
Macrophages as determined by microscopic analysis of H&E-stained serial sections.