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. 2023 Jan 18;9:12. doi: 10.1038/s41420-023-01320-5

Fig. 6. Inhibition of SPHK2 with ABC294640 protects the lung against LPS-driven oxidative injury in mice (n = 6).

Fig. 6

A Representative lung sections from PBS group, ABC294640 group, LPS group and LPS + ABC294640 group stained by H&E. B Lung injury score, C inflammatory cell count and D BALF protein concentration among different groups. E SOD content, F MPO activities, and G MDA levels were measure in lung tissue homogenates. Data were presented as the means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.005; ****p < 0.001.