Table 2.
Sample characteristics by OSA status and race.
| Black participants | White participants | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OSA+(n=24) | OSA-(n=166) | F/t/X2 | Sig | OSA+(n=230) | OSA-(n=962) | F/t/X2 | Sig | |||||
| Age mean(SD) | 69.1 | (7.5) | 68.4 | 8.6 | −0.39 | 0.348 | 70.36 | (7.6) | 69.83 | (8.4) | −0.88 | 0.190 |
| Female sex | 15 | 62.5% | 125 | 75.3% | 1.77 | 0.216 | 100 | 43.3% | 573 | 59.3% | 19.45 | <0.001 |
| Education | ||||||||||||
| Years {mean±SD} | 14.83 | (2.8) | 15.56 | (2.8) | 1.19 | 0.118 | 16.01 | (2.6) | 16.21 | (2.8) | 0.97 | 0.165 |
| <9 | Elementary School | 0 | 0.0% | 1 | 0.6% | 1.07 | 0.784 | 2 | 0.9% | 16 | 1.7% | 4.37 | 0.224 |
| 9-12 | High School | 6 | 25.0% | 32 | 19.3% | 23 | 10% | 104 | 10.8% | ||||
| 13-16 | College | 11 | 45.8% | 69 | 41.6% | 115 | 50% | 412 | 42.8% | ||||
| >17 | Graduate School | 7 | 29.2% | 64 | 38.6% | 90 | 39.1% | 430 | 44.7% | ||||
| Cognitive Status | ||||||||||||
| Normal Cognitive Status | 13 | 54.2% | 93 | 56.0% | 1.65 | 0.648 | 100 | 43.3% | 465 | 48.1% | 4.12 | 0.249 |
| Impaired, not MCI | 1 | 4.2% | 10 | 6.0% | 8 | 3.5% | 32 | 3.3% | ||||
| MCI | 9 | 37.5% | 46 | 27.7% | 89 | 38.5% | 306 | 31.7% | ||||
| Dementia | 1 | 4.2% | 17 | 10.2% | 34 | 14.7% | 163 | 16.9% | ||||
| APOE-e4 | ||||||||||||
| APOE e4 Carrier | 9 | 37.5% | 71 | 42.8% | 0.24 | 0.625 | 81 | 35.1% | 365 | 37.8% | 0.60 | 0.442 |
| Frequency of alleles | ||||||||||||
| e3/e3 | 11 | 45.8% | 65 | 39.2% | 1.28 | 0.937 | 127 | 55.0% | 516 | 53.4% | 2.73 | 0.741 |
| e3/e4 | 8 | 33.3% | 62 | 37.3% | 59 | 25.5% | 280 | 29.0% | ||||
| e3/e2 | 4 | 16.7% | 28 | 16.9% | 21 | 9.1% | 82 | 8.5% | ||||
| e2/e4 | 1 | 4.2% | 5 | 3.0% | 18 | 7.8% | 65 | 6.7% | ||||
| e4/e4 | 0 | 0.0% | 4 | 2.4% | 4 | 1.7% | 20 | 2.1% | ||||
| e2/e2 | 0 | 0.0% | 2 | 1.2% | 2 | 0.9% | 3 | 0.3% | ||||
| APOE-e4 allele degree | 0.41 | 0.814 | 1.40 | 0.496 | ||||||||
| No e4 allele | 15 | 62.5% | 95 | 57.2% | 150 | 64.9% | 601 | 62.2% | ||||
| One copy of e4 allele | 8 | 33.3% | 66 | 39.8% | 63 | 27.3% | 300 | 31.1% | ||||
| Two copies of e4 allele | 1 | 4.2% | 5 | 3.0% | 18 | 7.8% | 65 | 6.7% | ||||
| n=5 | n=34 | n=35 | n=129 | |||||||||
| Hippocampal Volume mean (SD) | 6.3 | (1.1) | 6.3 | (0.8) | −0.02 | 0.493 | 6.5 | (1.0) | 6.6 | (0.9) | 0.99 | 0.162 |
| n=5 | n=34 | n=35 | n=126 | |||||||||
| WMH Volume mean (SD) | 8.1 | (14.5) | 8.31 | (35.9) | 0.01 | 0.494 | 6.4 | (9.6) | 7.1 | (19.6) | 0.21 | 0.415 |
| n=0 | n=13 | n=13 | n=291 | |||||||||
| Abnormal Amyloid levels | 0 | 0.0% | 13 | 100% | - | - | 15 | 27.3% | 115 | 48.7% | 8.31 | 0.004 |
| n=24 | n=164 | n=210 | n=868 | |||||||||
| MOCA Total Score | 24.2 | (4.1) | 23.0 | (4.9) | −1.14 | 0.129 | 24.0 | (4.6) | 24.0 | (5.3) | 0.02 | 0.492 |
Data represented as n, % unless otherwise specified. *Indicates statistically different groups based on post hoc analyses. Individual variable sample sizes listed for those with more than 10% of sample missing data. WMH = White Matter Hyperintensities. Statistically significant associations bolded.