TABLE 2.

Group difference effects (MBI+ < MBI–) for FC within the DMN and salience network SN

Seed region	ROI (x, y, z)	Cluster p ‐value (FDR)
PCC (DMN)	MPFC (1, 55, –3)	.0037*
	LP (L) (–37, –77, 33)	.54
	LP (R) (47, –67, 29)	.54
ACC (SN)	AI (L) (–44, 13, 1)	.028*
	SMG (L) (–60, –39, 31)	.075
	SMG (R) ( 62, –35, 32)	.11
	AI (R) (47, 14, 0)	.11
	RPFC (L) (–32, 45, 27)	.90
	RPFC (R) (32, 46, 27)	.93

^*Cluster p‐FDR <.05.

Abbreviations: ACC, anterior cingulate cortex; AI, anterior insula; DMN, default mode network; FC, functional connectivity; FDR, false discovery rate; L, left; LP, lateral parietal; MBI, mild behavioral impairment; MPFC, medial prefrontal cortex; PCC, posterior cingulate cortex; R, right; ROI, region of interest; RPFC, rostral prefrontal cortex; SMG, supramarginal gyrus; SN, salience network.