TABLE 3.

Herbal Medicines other than G. biloba in the Treatment of Tinnitus.

Medicine herbs	Study design (trial registration)	Patients	Interventions	Outcomes
Açaí (Euterpe Oleracea Martius) Oppitz et al. (2022)	Double blind RCT (RBR-8z4mhq)	Chronic tinnitus (n = 30)	Patients received açai extract 100 mg or placebo	Mean difference from baseline THI -10.0 ± 6.4 and -8.8 ± 3.6
Korean red ginseng Kim et al. (2015)	Open-label RCT	Chronic tinnitus (n = 61)	Patients received Korean red ginseng 1,500 mg/day or 3,000 mg/day, or G. biloba extract 160 mg/day for 4 weeks	Mean difference from baseline THI 4.38 ± 2.31, 8.05 ± 2.33, and 4.05 ± 2.22
Gushen Pian Zhai et al. (2013)	Double blind RCT (Z20080046)	Non-hereditary acquired sensorineural deafness with associated tinnitus or simple tinnitus without hypoacusis (n = 120)	Patients received Gushen Pian 5 tablets (40 patients), Erlong Zuoci Pills (40 patients), or placebo (40 patients) for 4 weeks	Total effective rate, 89.2%, 74.3% and 30.8%; total relief rate, 59.5%, 57.1% and 5.1%
Bushen Huoxue Tongluo Zhang et al. (2022)	Assessor-blinded RCT	Chronic subjective tinnitus (n = 20)	Patients received Bushen Huoxue Tongluo granules and informative counseling, or informative counseling alone	The trial is ongoing. THI, tinnitus functional index, tinnitus sensation level, self-rated visual analogue scale on tinnitus loudness and annoyance, Pittsburgh Sleep Quality Index and adverse event