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. 2023 Jan 4;13:1089667. doi: 10.3389/fphar.2022.1089667

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Copyright © 2023 Abu-Serie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of DF(II) complexes on liver function parameters as well as histological assessment of their toxicity on tissues of the treated N groups (A) Liver function indexes (ALT, AST, and albumin) in healthy N group and the untreated and treated LC groups. Healthy N group was compared to the untreated and DF(II) complexes-treated LC groups, considering statistically significant at p ≤ 0.05*, ≤0.005**, and ≤0.001*** (B) H&E staining tissues of DF(II) NPs- and DF(II)-treated N groups compared to the untreated healthy N groups.