IC50 values of the gold(i)-NSAID complexes, 1–3, 5-fluorouracil, capecitabine, cisplatin, carboplatin, and salinomycin against HMLER cells, HMLER-shEcad cells, and HMLER-shEcad mammospheres.
| Compound | HMLER IC50/nM | HMLER-shEcad IC50/nM | Mammosphere IC50/μM |
|---|---|---|---|
| 1 | 190 ± 10 | 56 ± 1 | 2 ± 0.1 |
| 2 | 221 ± 3 | 138 ± 7 | 8 ± 1 |
| 3 | 183 ± 1 | 63 ± 6 | 8 ± 1 |
| 5-Fluorouracil | 41 050 ± 5303 | 49 100 ± 5940 | 15 ± 1 |
| Capecitabine | >100 000 | >100 000 | >133 |
| Cisplatina | 2565 ± 21 | 5645 ± 304 | 14 ± 2 |
| Carboplatina | 67 310 ± 2800 | 72 390 ± 7990 | 18 ± 1 |
| Salinomycina | 11 430 ± 420 | 4230 ± 350 | 19 ± 2 |