TABLE 3.

Implications of Clinical Recommendations With Grading of Recommendations, Assessment, Development, and Evaluation Certainty of Evidence and Strength of Recommendation to Stakeholders (29)

Stakeholder	Strong Recommendation	Conditional Recommendation
Patients	Most individuals in this situation would want the “recommended” course of action and only a small proportion would not	The majority of individuals in this situation would want the “suggested” course of action, but many would not
Clinicians	Most individuals should receive the “recommended” course of action	Recognize that different choices will be appropriate for different patients and that you must help each patient arrive at a management decision consistent with her or his values and preferences
Policy makers	The recommendation can be adapted as policy in most situations including for the use as performance indicators	Policy making will require substantial debates and involvement of many stakeholders. Policies are also more likely to vary between regions