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Inhibitory values of deazapurine related compounds against SGK1 and their IC50.
| Comp. | SGK1 % Inh@ 10 µM | IC50 (µM) | Structure | Comp. | SGK1 % Inh @10 µM | IC50 (µM) | Structure |
|---|---|---|---|---|---|---|---|
| GSK650394 | 92.6 | 0.1 |
|
GMH1.12 | 74.3 | 5.5 |
|
| VNG1.7 | 54.0 | 9.3 |
|
ERP2.14 | 52.6 | 6.4 |
|
| VNG1.52 | 60.5 | 2.4 |
|
ERP1.32 | 6.6 | – |
|
| VNG1.65 | 62.6 | 3.4 |
|
ERP1.22 | 21.9 | – |
|
| AEV1.40 | 65.3 | 6.5 |
|
ERP1.19 | 3.9 | – |
|
