Table 4.
The MIC (µg/ml) ranges of different antibiotics in various slowly growing mycobacterial species.
| Antibiotics | RIF | MXF | CLR | EMB | AMK | LZD | CFZ | INH |
|---|---|---|---|---|---|---|---|---|
|
M. kansasii MIC: n (%) |
0.125≥: 3 (6.5) 0.25: 7 (15.2) 1: 16 (34.7) 2: 12 (26.0) 4: 1 (2.1) 8: 1 (2.1) 16≤: 6 (13.0) |
0.25≥: 24 (52.1) 0.5: 2 (4.3) 1: 4 (8.6) 2: 10 (21.7) 4: 2 (4.3) 16: 4 (8.6) |
0.5≥: 11(23.9) 1: 1 (2.1) 4: 2 (4.3) 8: 4 (8.6) 16: 20 (43.4) 32≤: 8 (17.3) |
0.125 ≥: 2 (4.3) 0.25: 2 (4.3) 0.5: 2 (4.3) 1: 9 (19.5) 2: 7 (15.2) 4: 10 (21.7) 16: 14 (30.4) |
0.5≥: 14 (21.7) 1: 23 (50) 2: 2 (4.3) 4: 7 (15.2) |
0.5≥: 1 (2.1) 16≤:45(97.8) |
2≥:12(26.0) 8: 4 (8.6) 64≤:30(65.2) |
0.5≥: 1 (2.1) 1: 2 (4.3) 2: 11 (23.9) 4: 3 (6.5) 8: 4 (8.6) 16: 8 (17.3) 32≥: 17 (36.9) |
|
M. simiae MIC: n (%) |
16 | 0.25≥: 4 (19.0) 1: 2 (9.5) 2: 5 (23.8) 16: 10 (47.6) |
0.5≥:2(9.5) 8: 2 (9.5) 16: 12 (57.1) 32≤: 5 (23.8) |
0.125: 1 (4.7) 1: 2 (9.5) 2: 7 (33.3) 16: 11 (52.3) |
1: 18 (85.7) 4: 1 (4.7) 32≤: 2 (9.5) |
16< | 64: 6 (28.5) 64<: 15 (71.4) |
32< |
|
MAC MIC: n (%) |
2: 4 (40) 4: 1 (10) 8: 1 (10) 16≤: 4 (40) |
0.25≥: 6 (60) 1: 1 (10) 2: 2 (20) 16≤: 1 (10) |
0.5≥:2(20) 4: 2 (20) 8: 3 (30) 16: 2 (20) 32≤: 1 (10) |
0.125 ≥: 1 (10) 0.5: 1 (10) 2: 4 (40) 4: 1 (10) 8: 2 (20) 16: 1 (10) |
0.5≥: 6 (60) 1: 1 (10) 2: 1 (10) 4: 2 (20) |
16< | 2≥: 3 (30) 4: 1 (10) 16: 4 (40) 64≤: 2 (20) |
2: 1 (10) 4: 1 (10) 32≥: 8 (80) |
MIC: minimum inhibitory concentration; RIF: rifampin; MXF: moxifloxacin; CLR: clarithromycin; EMB: ethambutol; AMK: amikacin; LZD: linezolid; CFZ: clofazimine; INH: isoniazid; MAC: Mycobacterium avium complex.