Table 5.
The frequency of genotypic resistance determinants in phenotypically resistance isolates.
| SGM species | Antibiotics | Phenotypic resistance n (%) |
Genotypic resistance determinants |
|
|---|---|---|---|---|
| Without mutation n (%) | With mutation n (%) | |||
| M. kansasii (n = 46) | RIF | 20 (43.5) | 17 (85.0) | 3 (15.0%) |
| MXF | 6 (13.0) | 0 (0.0) | 6 (100.0) | |
| CLR | 8 (17.4) | 0 (0.0) | 8 (100.0) | |
| M. simiae (n = 21) | CLR | 5 (23.8) | 0 (0.0) | 5 (100.0) |
| MAC (n = 10) | CLR | 1 (10.0) | 0 (0.0) | 1 (100.0) |
RIF: rifampin; MXF: moxifloxacin; CLR: clarithromycin; MAC: Mycobacterium avium complex; SGM: slowly growing mycobacteria.