Table 3.
Brain regions with significant alterations in seed-based functional connectivity between adolescents with borderline personality disorder (BPD) and healthy controls (HCs) (voxel p < .001, cluster p < .05, FWE corrected).
| Seed point | Brain region | MNI peak coordinates | T | Cluster size | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Left lateral occipital | Frontal_Sup_R | 24 | 36 | −12 | 5.0159 | 331 |
| Right lateral occipital | Frontal_Inf_Orb_R | 36 | 27 | −21 | 10.148 | 767 |
| Frontal_Inf_Tri_R | 48 | 30 | 0 | 5.392 | 593 | |
| Cingulum_Ant_R | −12 | 42 | 9 | 4.4318 | 135 | |
| Left inferior temporal | Temporal_Inf_R | 48 | −12 | −33 | 6.6611 | 253 |
| Frontal_Inf_Orb_R | 51 | 24 | −6 | 4.9926 | 126 | |
| Right inferior temporal | Frontal_Inf_Orb_R | 36 | 30 | −21 | 7.1943 | 2802 |
| Temporal_Inf_L | −51 | −12 | −30 | 6.498 | 285 | |
| Left parahippocampal | Parietal_Sup_L | −18 | −75 | 57 | −4.6591 | 129 |
| Right precuneus | Frontal_Mid_L | −33 | 0 | 66 | −5.7415 | 173 |
| Parietal_Sup_L | −27 | −57 | 69 | −4.833 | 168 | |
Note: Ant, anterior; FWE, family-wise error; Inf, inferior; L, left; Mid, middle; MNI, Montreal Neurological Institute; Orb, orbital; R, right; Sup, superior; Tri, triangular.