Table 3.
In-vitro PIM-1 and PIM-2 kinase inhibition data of the most active compounds.
| Code | PIM-1 IC50 (µM) |
PIM-2 IC50 (µM) |
|---|---|---|
| 5b | 1.31 | 0.67 |
| 5c | 1 | 1.66 |
| 6e | 1.10 | 1.49 |
| 13a | 1.27 | – |
| 13c | 7.78 | – |
| 14a | 0.385 | – |
| Quercetin | 1.17 | 0.61 |
In-vitro PIM-1 and PIM-2 kinase inhibition data of the most active compounds.
| Code | PIM-1 IC50 (µM) |
PIM-2 IC50 (µM) |
|---|---|---|
| 5b | 1.31 | 0.67 |
| 5c | 1 | 1.66 |
| 6e | 1.10 | 1.49 |
| 13a | 1.27 | – |
| 13c | 7.78 | – |
| 14a | 0.385 | – |
| Quercetin | 1.17 | 0.61 |