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In vivo pterostilbene concentration vs. time profiles of the different samples (brain and plasma) after a single intravenous administration of (A) free pterostilbene solution (free Pt), (B) folate modified pterostilbene loaded micelles (F-Pt/M) at a dose of 3 mg/kg in rats. And (C) pterostilbene concentration in brain vs. time profiles of free Pt and F-Pt/M. Serial brain/blood samples were collected at 5, 15, 30, 45,60, 90,120 and 180 min. The data represent the mean ± SD (n = 3).
