Table 7.

Identified significant biomarker hub proteins in the continuation of the comorbidities.

Rank	Symbol	Name	Degree	Affiliated comorbidity
1	IL1B	Interleukin 1 beta	50	Hypertension, diabetes, obesity, and lung cancer.
2	CXCL8	C-X-C motif chemokine ligand 8	38	Hypertension, diabetes, obesity, and lung cancer.
3	FN1	Fibronectin 1	37	Hypertension, diabetes, obesity, and lung cancer.
4	MMP9	Matrix metallopeptidase 9	35	Hypertension, diabetes, obesity, and lung cancer.
5	CXCL10	C-X-C motif chemokine 10	32	Hypertension, diabetes, obesity, and lung cancer.
6	IL1A	Interleukin 1 alpha	21	Hypertension, diabetes, obesity, and lung cancer.
7	IRF7	Interferon regulatory factor 7	20	Diabetes, obesity, and lung cancer.
8	VWF	Von Willebrand factor	19	Hypertension, diabetes, obesity, and lung cancer.
8	CXCL9	C-X-C motif chemokine ligand 9	19	Hypertension, diabetes, obesity, and lung cancer.
10	ISG15	Interferon-stimulated gene 15	18	Hypertension and lung cancer.