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. 2023 Jan 4;613(7944):582–587. doi: 10.1038/s41586-022-05560-w

Fig. 1. Cas12a2 binary complex resembles an oyster and orders the crRNA.

Fig. 1

a, Domain organization of Cas12a2. b, Cryo-EM structure of Cas12a2 binary complex coloured by structural domain as in a. c, Atomic model of Cas12a2 binary complex. d, Putative 3′ seed region of crRNA. Seven bases from the 3′ end are ordered, and bases are solvent-exposed, probably acting as a seed for target RNA binding.