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. 2023 Jan 4;613(7944):582–587. doi: 10.1038/s41586-022-05560-w

Extended Data Fig. 1. Cryo-EM data analysis.

Extended Data Fig. 1

a, Gold standard Fourier Shell Correlation (FSC) curves for Cas12a2 binary complex. b, Euler plot for Cas12a2 binary complex. c, Directional FSC53 for Cas12a2 binary complex. d, Cas12a2 binary complex colored by local resolution. Left – surface, right, cut-through. e, Map-to-model FSC for Cas12a2 binary complex. f, Gold standard FSC for Cas12a2 ternary complex. g, Euler plot for Cas12a2 ternary complex. h, Directional FSC for Cas12a2 ternary complex. i, Cas12a2 ternary complex colored by local resolution. Left – surface, right, cut-through. j, Map-to-model FSC for Cas12a2 ternary complex. k, Gold standard FSC for Cas12a2 quaternary complex. l, Euler plot for Cas12a2 quaternary complex. m, Directional FSC for Cas12a2 quaternary complex. n, Cas12a2 quaternary complex colored by local resolution. Left – surface, right, cut-through. o, Map-to-model FSC for Cas12a2 quaternary complex.