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. 2023 Jan 4;613(7944):582–587. doi: 10.1038/s41586-022-05560-w

Extended Data Fig. 2. Comparison of Cas12a2 and Cas12a.

Extended Data Fig. 2

a - c, Cas12a2 binary complex (a), active quaternary complex (b) colored by structural domain (c). d – f, Cas12a binary complex (d), active ternary complex (e) colored by structural domain (f). g, Overlay of 5′ crRNA handle, WED, RuvC and PI domains of Cas12a2 (colored) and Cas12a (transparent grey).