Extended Data Fig. 1. Variants known to cause disease with recessive inheritance are found at a higher MAF in Finnish Europeans than in other Europeans.

We show MAF of 2,419 unique likely pathogenic variants (source: ClinVar²⁰) in 10,824 individuals from FIN and 10,824 from NFE populations (source: gnomAD²⁴). a, All 2,419 variants (violin plot). b, All 2,419 variants (histogram). In c we subset to 133 variants in Finnish disease heritage genes^2,9. Violin plots are scaled to have the same area. Box plots within violins show the 1st, 2nd and 3rd quartiles of the MAF distribution; whiskers maximally extend to 1.5 interquartile range.