Table 3.
Factors associated with Ang 1–7 assessed by linear regression analysis. Both univariate and multivariate regression analyses are shown.
| Parameters | Univariate model | Multivariate model | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | aHR | 95% CI | p-value | |
| Age, years | 1.10 | −0.61 to 2.81 | 0.195 | – | – | – |
| Sex, male | 14.7 | −23.01 to 52.42 | 0.428 | – | – | – |
| MELD, points | 2.10 | −0.78 to 5.00 | 0.145 | – | – | – |
| HVPG, mmHg | 2.61 | 0.69 to 4.52 | 0.010 | 2.57 | 0.60 to 4.54 | 0.013 |
| VWF, % | 0.15 | 0.01 to 0.30 | 0.049 | 0.01 | −0.23 to 0.26 | 0.905 |
| IL-6, pg mL−1 | 0.21 | −0.89 to 1.31 | 0.697 | – | – | – |
| dACLD, yes | 7.67 | 1.65 to 13.70 | 0.015 | 2.96 | −8.15 to 14.05 | 0.586 |
Ang angiotensin, HVPG hepatic venous pressure gradient, IL-6 interleukin-6, LSM liver stiffness measurement, MELD model for end-stage liver disease, vWF von Willebrand factor antigen.