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. 2022 Nov 11;60(2):732–748. doi: 10.1007/s12035-022-03111-y

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Comparison of absolute protein expression levels of the transporters in the crude membrane fraction of a isolated brain microvessels of TgF344-AD rats (n = 6) [28] versus 5xFAD mice from the present study (n = 6); b isolated brain microvessels of WT rats (n = 6) [28] versus 8-month-old WT mice from the present study (n = 6); c the brain cortices of TgF344-AD rats (n = 8) [28] versus 5xFAD mice from the present study (n = 12); d the brain cortices of WT rats (n = 5) [28] versus 8-month-old WT mice from the present study (n = 14); e the brain cortices of female APdE9 mice (n = 4) [29] versus female 5xFAD mice from the present study (n = 12); f the brain cortices of female 8-month-old WT mice (n = 5) from the present study versus female 16–17-month-old WT mice (n = 14) [29]. The top and bottom dashed lines represent a twofold higher or lower protein expression, respectively, between the studied groups. Data are expressed as mean ± SD