Table 2.
Results of the univariate and multivariate Cox proportional hazards regression analysis
| Variable | Univariate models | Multivariate model | ||||
|---|---|---|---|---|---|---|
| p value | HR | (95% CI) | p value | HR | (95% CI) | |
| cN positive | 0.011 | 2.7 | (1.3, 6.0) | 0.029 | 2.6 | (1.1, 6.1) |
| ypN positive | < 0.001 | 7.9 | (3.7, 17.0) | 0.001 | 5.5 | (2.0, 15.1) |
| Positive response status | < 0.001 | 0.2 | (0.1, 0.5) | 0.720 | 0.7 | (0.1, 3.9) |
| ypT (0–1 vs. 2,3,4) | 0.005 | 3.1 | (1.4, 6.8) | 0.309 | 1.9 | (0.6, 6.2) |
| Resection margins (R1 vs. R0) | 0.007 | 4.4 | (1.5, 13.0) | 0.830 | 0.9 | (0.3, 2.9) |
Hazard ratios (HR) for cancer-specific death are shown with their 95% confidence intervals (CI) and corresponding p values of the Wald statistic from the models
p values < 0.05 were considered statistically significant
cN clinical lymph node status, pN pathological lymph node status, ypT pathological T stage after chemotherapy and cystectomy,