. 2022 Nov 20;46(1):92–99. doi: 10.1002/clc.23941

Table 3.

Prevalence of diseases according to OSA clinical subtypes with CMD risk

Prevalent disease (%)	ES (very high‐risk) N = 352	ModSwDS (high‐risk) N = 182	ModS (medium‐risk) N = 826	MinS (low‐risk) N = 123	p Value
Type 2 diabetes, N	87 (24.7)	45 (24.7)	112 (13.6)	15 (12.2)	<.001^a ^, ^b ^, ^c ^, ^d
Hyperlipidemia, N	188 (53.4)	82 (45.1)	348 (42.1)	37 (30.1)	<.001^a ^, ^b ^, ^c ^, ^e
Hypertension, N	213 (61.5)	106 (58.2)	431 (52.2)	57 (46.3)	=.010 ^c ^, ^a ^, ^b
CHD, N	88 (25.0)	39 (21.4)	112 (13.6)	13 (10.6)	<.001^d ^, ^c ^, ^a ^, ^b
HF, N	13 (3.7)	22 (12.1)	35 (4.2)	10 (8.1)	<.001^f ^, ^d ^, ^b
Asthma, N	12 (3.4)	13 (7.1)	23 (2.8)	8 (6.5)	=.014^d ^, ^e
COPD, N	17 (4.8)	21 (11.5)	35 (4.2)	8 (6.5)	<.001^f ^, ^d
RE, N	56 (15.9)	30 (16.5)	84 (10.2)	12 (9.8)	=.010^d ^, ^a
Rhinosinusitis, N	134 (38.1)	36 (19.8)	234 (28.3)	23 (18.7)	<.001^f ^, ^d ^, ^a ^, ^b ^, ^e
Pharyngitis, N	152 (43.2)	54 (29.7)	268 (31.8)	25 (20.3)	<.001^f ^, ^a ^, ^b ^, ^e
Anxiety, N	10 (2.8)	17 (9.3)	16 (1.9)	4 (3.3)	<.001^d ^, ^c ^, ^f
Stroke, N	28 (8.0)	25 (13.7)	65 (7.9)	10 (8.1)	=.076
Arrhythmia, N	32 (9.1)	25 (13.7)	62 (7.5)	9 (7.3)	>.05
Hypothyroidism, N	12 (3.4)	3 (1.6)	14 (1.7)	1 (0.8)	>.05
Depression, N	4 (1.1)	1 (0.5)	7 (0.8)	3 (2.4)	>.05

Note: p Value from χ ² test comparing variable across subtypes. The data is presented in positive form unless otherwise specified. Significant differences in pairwise comparisons (p < .05).

Abbreviations: CHD, coronary heart disease; CMD, cardiovascular and metabolic diseases; COPD, chronic obstructive pulmonary disease; ES, excessively sleepy; HF, heart failure; MinS, minimally symptomatic; ModS, moderately sleepy; ModSwDS, moderately sleepy with disturbed sleepy; N, sample size; OSA, obstructive sleep apnea; RE, reflux esophagitis.

^{^a}

ES vs. ModS.

^{^b}

ES vs. MinS.

^{^c}

ModSwDS vs. MinS.

^{^d}

ModSwDS vs. ModS.

^{^e}

ModS vs. MinS.

^{^f}

ES vs. ModSwDS.