Table 1.
Baseline Characteristics of the ADAMPA Trial Patients (Complete Cases)
| Total (N=312) |
Intervention (N=156) | Control (N=156) | p value | |
|---|---|---|---|---|
| Men, n (%) | 146 (46.8%) | 70 (44.9%) | 76 (48.7%) | 0.50 |
| Age, years, mean (SD) | 64.4 (1.0) | 64.8 (9.7) | 63.9 (10.3) | 0.40 |
| Systolic blood pressure, mmHg, mean (SD) | 155.2 (12.9) | 155.2 (13.1) | 155.2 (12.8) | 0.96 |
| Diastolic blood pressure, mmHg, mean (SD) | 90.1 (8.0) | 89.7 (7.9) | 90.6 (8.1) | 0.30 |
| Body mass index, n (%) | ||||
| Normal (18–24 kg/m2) | 48 (15.3%) | 26 (16.7%) | 22 (14.1%) | 0.68 |
| Overweight (25–30 kg/m2) | 133 (42.6%) | 63 (40.4%) | 70 (44.9%) | |
| Obese (≥30 kg/m2) | 130 (41.7%) | 66 (42.3%) | 64 (41.0%) | |
| Body mass index, mean (SD) | 29.8 (4.9) | 29.9 (5.2) | 29.6 (4.7) | 0.67 |
| Level of education, n (%) | ||||
| No qualification | 20 (6.4%) | 13 (8.3%) | 7 (4.5%) | 0.53 |
| Primary education | 128 (41.0%) | 64 (41.0%) | 64 (41.0%) | |
| Secondary education | 103 (33.0%) | 51 (32.7%) | 52 (33.3%) | |
| University degree or higher | 61 (19.6%) | 28 (18.0%) | 33 (21.6%) | |
| Marital status, n (%) | ||||
| Single | 21 (6.7%) | 9 (5.8%) | 12 (7.7%) | 0.41 |
| Married | 216 (69.2%) | 105 (67.3%) | 111 (71.2%) | |
| Divorced | 28 (9.0%) | 18 (11.5%) | 10 (6.4%) | |
| Widowed | 47 (15.1%) | 24 (15.4%) | 23 (14.7%) | |
| Employment status, n (%) | ||||
| Permanent work | 93 (29.8%) | 43 (27.6%) | 50 (32.1%) | 0.19 |
| Temporary work | 6 (1.9%) | 3 (1.9%) | 3 (1.9%) | |
| Housewife | 36 (11.5%) | 17 (10.9%) | 19 (12.2%) | |
| Unemployed | 18 (5.8%) | 14 (9.0%) | 4 (2.5%) | |
| Pensioner | 159 (51.0%) | 79 (50.6%) | 80 (51.3%) | |
| Smoking, n (%) | 64 (20.5%) | 28 (18.0%) | 36 (23.1%) | 0.26 |
| Sedentarism, n (%) | 138 (44.2%) | 78 (50.0%) | 60 (38.5%) | 0.040 |
| HRQoL (EQ5D), mean (SD) | 0.85 (0.20) | 0.85 (0.23) | 0.86 (0.17) | 0.48 |
| Comorbidities, n (%) | ||||
| Diabetes | 75 (24.0%) | 38 (24.4%) | 37 (23.7%) | 0.90 |
| Cerebrovascular disease | 10 (3.2%) | 4 (2.6%) | 6 (3.9%) | 0.52 |
| Angina | 2 (0.6%) | 1 (0.6%) | 1 (0.6%) | 1.00 |
| Acute myocardial infarction | 4 (1.3%) | 3 (1.9%) | 1 (0.6%) | 0.31 |
| Peripheral artery disease | 5 (1.6%) | 2 (1.3%) | 3 (1.9%) | 0.65 |
| Chronic kidney disease | 18 (5.8%) | 9 (5.8%) | 9 (5.8%) | 1.00 |
| Years from onset of hypertension, mean (SD) | 11.1 (9.3) | 11.1 (9.6) | 11.0 (9.0) | 0.92 |
| N antihypertensive drugs, mean (SD) | 1.8 (0.9) | 1.9 (0.9) | 1.8 (0.9) | 0.43 |
| N concomitant treatmentsa, mean (SD) | 2.35 (2.3) | 2.25 (1.9) | 2.5 (2.5) | 0.43 |
| Home blood pressure monitoring, n (%) | 87 (27.9%) | 38 (24.4%) | 49 (31.4%) | 0.17 |
SD, standard deviation; HRQoL, health-related quality of life; EQ5D, EuroQol 5D-3L
aIn addition to antihypertensive medications