Table 3.

Odds ratios (ORs) for decreasing values of IGFBP-2, adiponectin and IGFBP-1 measured at baseline and included in the same regression model in the association to development of prediabetes and type 2 diabetes at follow-up in women and men.

	NGT	Prediabetes				Type 2 diabetes
	n	n	ORc	95% CI	p	n	ORc	95% CI	p
WOMEN
Model 1a	200	133				55
IGFBP-2, 2log			3.19	1.96-5.19	<0.0001		3.03	1.50-6.13	0.0021
Adiponectin, 2log			2.74	1.69-4.42	<0.0001		4.90	2.29-10.51	<0.0001
IGFBP-1, 2log			1.47	0.99-2.16	0.0535		2.39	1.30-4.37	0.0499
Model 2b	200	133				55
IGFBP-2, 2log			2.70	1.59-4.57	0.0002		3.04	1.23-7.52	0.0158
Adiponectin, 2log			2.40	1.45-3.97	0.0007		7.75	2.94-20.43	<0.0001
IGFBP-1, 2log			1.32	0.86-2.02	0.2070		1.39	0.69-2.79	0.3629
MEN
Model 1a	277	164				98
IGFBP-2, 2log			1.28	0.85-1.95	0.2392		1.36	0.83-2.25	0.2247
Adiponectin, 2log			1.06	0.71-1.57	0.7768		1.43	0.89-2.29	0.1423
IGFBP-1, 2log			3.21	2.33-4.43	<0.0001		2.86	1.97-4.15	<0.0001
Model 2b	277	164				98
IGFBP-2, 2log			1.21	0.77-1.89	0.4139		1.60	0.93-2.77	0.0924
Adiponectin, 2log			0.98	0.64-1.48	0.9068		1.25	0.76-2.05	0.3901
IGFBP-1, 2log			3.05	2.18-4.25	<0.0001		2.62	1.73-3.96	<0.0001

^aModel 1: adjusted for age (36-40, 41-45, 46-50, 51-56 yrs)

^bModel 2: adjusted for age, BMI (<25.0, 25.0-29.9, ≥30.0), physical activity during leisure time (sedentary, moderate, regular exercise), smoking (never, former, current), socioeconomic status (low, middle, high, self-employed) and blood pressure (normal blood pressure and no hypertension treatment vs high blood pressure and/or hypertension treatment).

^cOR for the association between glucose tolerance and decreasing values of the variable.