Table 2.
Perioperative variables and infection status.
| Total (N = 83) | NIAC (N = 66) | IAC (N = 17) | Value of p | |
|---|---|---|---|---|
| Surgical diagnosis | 0.462 | |||
| Tumor | 37(44.6) | 30(45.5) | 7(41.2) | |
| Gastrointestinal perforation without tumor | 19(22.9) | 13(19.4) | 6(35.3) | |
| Postoperative gastrointestinal anastomosis leakage | 12(14.5) | 9(13.6) | 3(17.6) | |
| Intestinal obstruction without tumor | 5(6.0) | 5(7.6) | 0(0.0) | |
| Othersa | 10(12.0) | 9(13.6) | 1(5.9) | |
| Site of abdominal surgery | 0.001 | |||
| Upper gastrointestinal tract | 23 (27.7) | 13 (19.7) | 10 (58.8) | |
| Non-upper gastrointestinal tract | 60 (72.3) | 53 (80.3) | 7 (41.2) | |
| Surgery type | 1.000 | |||
| Emergency | 64 (77.1) | 51 (77.3) | 13 (76.5) | |
| Elective | 19 (22.9) | 15 (22.7) | 4 (22.9) | |
| ASA classification IV or V | 34 (41.0) | 29 (43.9) | 5 (29.4) | 0.277 |
| ICU admission | ||||
| APACHE II score | 15 (11–19) | 15 (11–19) | 17 (12–20) | 0.432 |
| SOFA score | 6 (4–9) | 6.5 (4–9) | 6 (4–8.5) | 0.75 |
| Temperature, °C | 37.4 (36.7–37.9) | 37.4 (36.7–37.9) | 37.5 (36.8–38.0) | 0.631 |
| WBC (×109/L) | 9.8 (6.8–14.1) | 10.1 (8.0–14.1) | 8.4 (4.4–14.4) | 0.147 |
| NE, % | 89.5 (85.2–93.1) | 88.2 (84.6–92.6) | 92.0 (89.0–94.3) | 0.037 |
| PCT (ng/ml)b | 3.8 (1.0–15.1) | 4.0 (0.6–15.9) | 3.2 (1.4–7.4) | 0.909 |
| CRP (ng/ml)c | 133.3 (80.2–193.7) | 142.0 (84.8–196.0) | 69.3 (57.1–159.5) | 0.088 |
| Antifungal treatment | 53 (63.9) | 37 (56.1) | 16 (94.1) | 0.004 |
| Initial antifungal treatment d | 0.001 | |||
| Preventive therapies | 2/53 (3.8) | 2/37 (5.4) | 0/16 (0.0) | |
| Empirical therapies | 42/53 (79.2) | 33/37 (89.2) | 9/16 (56.3) | |
| Preemptive therapies | 3/53 (5.7) | 2/37 (5.4) | 1/16 (33.3) | |
| Target therapies | 6/53 (11.3) | 0/37 (0.0) | 6/16 (37.5) |
Results are presented as mean ± SD or median (interquartile range), or n (%). aOthers include intestinal ischemia, acute pancreatitis, choledocholithiasis, acute appendicitis, intra-abdominal hemorrhage, and postoperative intra-abdominal infection; bN = 80; cN = 62; dTwo patients began antifungal treatment before percutaneous drainage, and one patient began antifungal treatment before ICU admission. ASA, American Society of Anesthesiology; APACHE, acute physiology and chronic health evaluation; SOFA, sepsis-related organ failure assessment; WBC, white blood cell, NE neutrophils; CRP, C-reaction protein; PCT, procalcitonin.