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. 2023 Jan 5;13:1070688. doi: 10.3389/fmicb.2022.1070688

Table 3.

Risk factors of IAC.

Univariate logistics Multivariate logistics
OR (95% CI) Value of p OR (95% CI) Value of p
Age ≥75 years 1.004 (0.345–2.920) / / 0.995
Male 3.889 (1.012–14.819) 0.071 4.504 (0.877–23.117) 0.047
BMI >25 kg/m2 0.331 (0.109–1.007) 0.667 1.410 (0.295–6.735) 0.051
Upper gastrointestinal surgery 5.824 (1.862–18.221) 0.007 6.119 (1.635–22.896) 0.002
Emergency 0.956 (0.271–3.369) / / 0.944
ASA IV or V 0.532 (0.168–1.681) / / 0.282
Underlying diseases
Solid tumor 0.686 (0234–2.009) / / 0.492
Diabetes mellitus 0.887 (0.254–3.093) / / 0.851
COPD 0.969 (0.101–9.276) / / 0.978
Hypertension 1.714 (0.582–5.051) / / 0.328
Coronary heart disease 1.200 (0.291–4.949) / / 0.801
Congestive heart failure 2.000 (0.170–23.461) / / 0.581
Arrhythmia 3.512 (0.953–12.947) 0.063 4.739 (0.920–24.416) 0.059
Cerebrovascular disease 1.627 (0.287–9.216) / / 0.582
APACHE IIa 1.034 (0.943–1.135) / / 0.474
SOFAa 0.968 (0.812–1.155) / / 0.721
Temperaturea, °C 1.083 (0.579–2.027) / / 0.803
WBCa, ×109/L 0.939 (0.848–1.041) / / 0.231
NE% > 90% a 3.692 (1.164–11.710) 0.009 6.665 (1.612–27.412) 0.027
PCTa,b, ng/ml 0.979 (0.925–1.036) / / 0.462
Recurrent gastrointestinal perforations, perforations untreated for more than 24 h, or both 2.488 (0.822–7.535) 0.26 2.144 (0.568–8.085) 0.107
Recurrent abdominal surgery within 30 days 0.618 (0.158–2.415) / / 0.489
Postoperative suspected or confirmed gastrointestinal anastomosis leakage 1.302 (0.398–4.261) / / 0.663
Septic shock 0.655 (0.225–1.910) / / 0.438

aAt ICU admission; bN = 80; BMI, body mass index; ASA, American Society of Anesthesiology; COPD, chronic obstructive pulmonary diseases; SOFA, sepsis-related organ failure assessment; APACHE, acute physiology and chronic health evaluation; WBC, white blood cell; NE, neutrophils; CRP, C-reaction protein; PCT, procalcitonin.