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. 2023 Jan 5;9:1091768. doi: 10.3389/fcvm.2022.1091768

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Copyright © 2023 Hashemi, Doeblin, Blum, Weiss, Schneider, Korosoglou, Beyer, Pieske, Edelmann and Kelle.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MyoHealth score at rest (A) and under stress (B) in healthy controls, controls with CV risk factors and HFpEF patients. CMR, cardiovascular magnetic resonance imaging; HG, handgrip exercise; NS, statistically not significant. Preserved regional strain values are blue, altered regional strain values are green. Color code reflects that early affected regions are primarily septal segments. In the at risk group the altered septal segments improve during HG stress, reflected by a color change from green to blue.