TABLE 1.
Baseline characteristics.
| Parameters | Controls (n = 12) |
At risk (n = 7) |
HFpEF (n = 19) |
P-value |
| Age – median [IQR], years | 59.00 [54.75–65.00] | 67.00 [62.00–72.00] | 78.00 [75.00–82.00] | <0.01* |
| Female sex – no. (%) | 6 (50.00) | 4 (57.14) | 9 (47.37) | 0.914 |
| LVEF – median [IQR], % | 63.00 [59.22–64.70] | 61.52 [57.88–64.58] | 61.12 [58.17–64.17] | 0.888 |
| LA area – median [IQR], cm2 | 20.00 [16.50–22.75] | 21.00 [19.00–21.00] | 22.50 [16.75–25.00] | 0.73 |
| NT-proBNP – median [IQR]), pg/dL | 66.00 [50.50–88.00] | 114.00 [58.50–175.50] | 314.00 [266.00–617.00] | <0.01* |
| hs-TroponinT – median [IQR], (ng/l) | 6.00 [4.00–7.50] | 8.00 [5.5–10.00] | 13.50 [9.00–20.00] | 0.02* |
| eGFR – median [IQR]), mL/min/1.73 m2 | 86.00 [71.50–90.00] | 82.00 [72.50–85.50] | 74.00 [60.25–82.75] | 0.06 |
| Coronary artery disease – no. (%) | 0 (0) | 0 (0) | 12 (66.67) | <0.01* |
| Arterial hypertension [n (%)] | 4 (33.33) | 3 (42.86) | 17 (89.47) | <0.01* |
| Diabetes – no. (%) | 0 (0) | 3.00 (42.86) | 7.00 (36.84) | 0.04* |
| Dyslipidemia – no. (%) | 2.00 (16.67) | 2.00 (28.57) | 12 (66.67) | 0.02* |
eGFR, estimated glomerular filtration rate; IQR, interquartile range (first quartile – third quartile); LV, left ventricular; LVEF, left ventricular ejection fraction; N, number. *Statistically significant. Further details on the baseline characteristics described by Blum et al. (11).