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. 2023 Jan 5;9:1026298. doi: 10.3389/fmed.2022.1026298

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Copyright © 2023 Ning, Garg, Mayer, Schick, Bracht, Barth, Weiss, Li, Schneider and Schneider.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Influence of obesity on monocytes in diabetic (D) patients with or without sepsis status. Distribution changes in the percentage of monocytes among the total leukocyte population (A) and the percentage of CD14⁺ monocytes (B) and CD33⁺ monocytes among the monocyte population (C). (D) Surface phenotype expression of CD16 on positive monocytes determined by mean fluorescence intensity (MFI). Data are presented by scatter with bar plots. Due to the small sample sizes, the non-obese and obese groups were not divided into sepsis (non-obese, n = 9; obese, n = 13) and septic shock (non-obese, n = 4; obese, n = 11) subgroups, rather presented as a combined “septic” group. Results are medians with interquartile range. Mann-Whitney U-test was used to analyze the differences between two groups. Significant difference is marked by *p < 0.05, **p < 0.01, and ***p < 0.001.