. 2022 Dec 23;4:100101. doi: 10.1016/j.crtox.2022.100101

Table 7.1.

Synthetic lung surfactant formulations. Each ingredient is categorized into a general class and listed by both abbreviated and full name. Columns under “Synthetic Lung Surfactant Formulation” represent different individual commercial or experimental formulations. Acronyms include artificial lung expanding compound (ALEC); Chiesi Farmaceutici 5633 (CHF5633), Forbes group of King’s College London (F-KCL).

Class	Ingredient	Formula	Full Name
Class	Ingredient	Formula	Full Name	ALEC	Exosurf	Surfaxin	Venticute	CHF5633	Minisurf	F-KCL
Lipid	DPPC	C₄₀H₈₀NO₈P	dipalmitoyl phosphatidylcholine	✓	✓	✓	✓	✓	✓	✓
	DPPG	C₃₈H₇₄NaO₁₀P	dipalmitoyl phosphatidylglycerol							✓
	POPC	C₄₂H₈₂NO₈P	palmitoyloleoyl phosphatidylcholine						✓
	POPG	C₄₀H₇₇O₁₀P	palmitoyloleoyl phosphatidylglycerol	✓		✓	✓	✓	✓
	Cho.	C₂₇H₄₆O	cholesterol							✓
Fatty Acid	Pal. Aci.	C₁₆H₃₂O₂	palmitic acid			✓	✓
Fatty Alcohol	Cet. Alc.	C₁₆H₃₄O	1-hexadecanol		✓
Polymer	Tyl.	C₁₇H₂₈O₃	tyloxapol		✓
Protein	IgG		immunoglobulin G							✓
	Alb.		albumin							✓
	Tra.		transferrin							✓
	aSP-B		surfactant protein B analog					✓
	aSP-C		surfactant protein C analog					✓
	rSP-C		recombinant surfactant protein C				✓