FIGURE 4.
Comparisons of the percentages of total NETs (A) and uncitrullinated NETs (B) formed after stimulation of healthy volunteer neutrophils with plasma from women delivering normal pregnancies (NP) or preeclampsia (PE) with and without inhibition by DPI. (A) NP without DPI 26.54% [25.48; 34.70]; NP with DPI 17.12% [5.86; 24.08]. PE without DPI 32.57% [29.99; 38.01]; PE with DPI 23.08% [22.44; 31.03]. (B) NP without DPI 12.80% [9.05; 18.23], NP with DPI 5.76% [1.98; 8.60]. PE without DPI 20.49% [14.58; 21.58]; PE with DPI 10.54% [7.83; 11.87]. (C) NP without DPI 15.56% [12.52; 19.63], NP with DPI 7.21% [1; 19.30]. PE without DPI 13.44% [9.63; 23.40]; PE with DPI 16.01% [11.68; 20.93]. DPI-: without inhibition by DPI; DPI+: with inhibition by DPI. Results are represented with their medians and interquartile ranges [Q1; Q3]. DPI: diphenyleiodonium. The Bonferroni correction with a cut-off at 0.025 was applied to take into account the multiplicity of tests. *p < 0.025, **p < 0.01, ***p < 0.001.