Fig. 5.

In vivo antibacterial capacity on mice subcutaneous infection model. (A) Experimental design and treatment protocols (created with BioRender.com). (B) Photographs of the MuRSA-infected abscesses of mice that were treated with different preparations for 11 consecutive days. (C) Curves showing wound areas after various treatments (wound area on the day after infection was used as 100%). (D) Curves show the body weight throughout the treatment process. (E) IL-6 and (F) TNF-α levels in wound tissue on the ninth day (n ​= ​6). (G) Lymphocyte count, (H) red blood cell count, and (I) neutrophil percentage in mice blood at the ninth day (n ​= ​6). (J) Photographs of bacterial colonies obtained from infected tissues of mice on the ninth day and bacteria colonies were counted by Image J (K) (n ​= ​6). (L–M) Representative images of wound tissue after H&E and Masson staining. (N) Fluorescent images of wound tissue after staining with anti-MPO antibody, in which the green and blue indicate neutrophil infiltration and nucleus respectively. Data are presented as the mean ​± ​SD: ∗p ​< ​0.05, ∗∗p ​< ​0.01, ∗∗∗p ​< ​0.001.