Fig. 6.

In vivo antibacterial capacity in mice wound infection model. (B) Experimental design and treatment protocols (created with BioRender.com). (A) Photographs of the MuRSA-infected wounds of mice that were treated with different preparations for nine consecutive days. (C) Curves showing wound areas after various treatments (wound area on the day after infection was used as 100%) (n ​= ​6). (D) Photographs of bacterial colonies obtained from infected tissues of mice on the ninth day. (E–F) Representative images of wound tissue after H&E and Masson staining. (G) Fluorescent images of wound tissue after staining with anti-F4/80 antibody, in which the red and blue fluorescent signals indicate macrophage and nucleus respectively. (H) TNF-α and (I) IL-6 levels in wound tissue on the ninth day (n ​= ​6). Data are presented as the mean ​± ​SD: ∗p ​< ​0.05, ∗∗p ​< ​0.01, ∗∗∗p ​< ​0.001.