Table 2.
The hallmarks of the perinatal impacts of the described emerging and re-emerging infectious diseases.
| Disease | Mode of transmission | Hallmarks of the perinatal outcomes |
|---|---|---|
| Influenza virus disease | Droplets (coughing and sneezing), close contact. | PTB; SGA; Low Apgar score at birth. |
| Ebola virus disease | Direct contact with body fluids (blood, vomit, breastmilk, semen, sweat, urine and stool). | Maternal death; fetal loss; Pregnancy-associated hemorrhages; stillbirth; spontaneous abortions; neonatal death. |
| Measles disease | Direct contact with infectious droplets, airborne (breathes, sneezes, coughs). | Spontaneous abortions; PTB; fetal death; congenital infections. |
| Pertussis disease | Close contact, respiratory secretions (coughing and sneezing) | Neonatal death |
| Zika virus disease | vector transmission (mosquito: Aedes species), blood borne, sexual transmission | Microcephaly; Congenital malformations. |
| MERS-CoV disease | Close contact, respiratory secretions (coughing), animal-to-human transmission (camels) | Maternal death; PTB; stillbirth. |
| COVID-19 disease | Close contact, droplet, airborne, fomite, fecal-oral, blood-borne, mother-to-child, and animal-to-human transmission | PTB; Stillbirth; LBW, SGA |
PTB, Preterm Births; LBW, Low Birth Weight; SGA, Small for Gestational Age.