Table 2.
Statistical analysis of demographic parameters and basal values of biochemical laboratory parameters in cholangiocarcinoma (CCA) only and liver cirrhosis (LC) with CCA groups
| Parameters | CCA only (n = 23) | CCA with LC (n = 17) | P value |
|---|---|---|---|
| Age (years) | 53.6 ±7.4 | 59.4 ±4.9 | 0.007 |
| Sex (M/F) | 18/5 | 11/6 | 0.343 |
| Hemoglobin (g/dl) | 10.9 ±1.4 | 11 ±1.5 | 0.778 |
| WBCs (103/µl) | 10.8 ±8.3 | 13.9 ±4.2 | 0.165 |
| Platelets (103/µl) | 215 ±90.5 | 281.2 ±88.9 | 0.246 |
| ALT (U/l) | 66.87 ±41.45 | 66.18 ±58.69 | 0.290 |
| AST (U/l) | 122.83 ±217.18 | 156.41 ±234.38 | 0.432 |
| ALP (U/l) | 416.61 ±503.51 | 336.18 ±180.18 | 0.914 |
| GGT (U/l) | 391.70 ±224.14 | 333.0 ±320 | 0.156 |
| Total bilirubin (mg/dl) | 17.53 ±7.12 | 16.15 ±8.23 | 0.533 |
| Direct bilirubin (mg/dl) | 14.43 ±6.26 | 12.43 ±6.30 | 0329 |
| Albumin (g/dl) | 3.02 ±0.68 | 2.71 ±0.74 | 0.179 |
| Total protein (g/dl) | 6.47 ±1.09 | 6.58 ±1.39 | 0.795 |
| Urea (mg/dl) | 41.87 ±28.20 | 49.86 ±26.49 | 0.369 |
| Creatinine (mg/dl) | 1.14 ±0.65 | 1.0 ±0.47 | 0.356 |
| AFP (ng/ml) | 6.2 ±6 | 5.9 ±5.8 | 0.894 |
| CA19-9 (U/ml) | 2480.6 ±2727.7 | 1748.9 ±2162.2 | 0.367 |
WBCs – white blood cell count, AST – aspartate aminotransferase, ALT – alanine aminotransferase, ALP – alkaline phosphatase, GGT – γ-glutamyl transferase
AFP – α-fetoprotein, CA 19-9 – cancer antigen 19.9/carbohydrate antigen
Statistically significant at p > 0.05