Table 2.
Dyspnea Interventions Grouped by Baseline MRC.
| MRC 1 (n = 4) | MRC 2 (n = 3) | MRC 3 (n = 24) | MRC 4 (n = 32) | MRC 5 (n = 18) | Overall | ||
|---|---|---|---|---|---|---|---|
| Pulmonary rehabilitation | |||||||
| Initiated prior to MDC | Total patients, n (%) | 0 (0) | 0 (0) | 3 (12.5) | 4 (12.5) | 0 (0) | 7 (8.6) |
| Referred prior to MDC, n | 0 | 0 | 1 | 1 | 0 | 2 | |
| Completed ≤1 year prior to MDC, n | 0 | 0 | 2 | 3 | 0 | 5 | |
| Referred during MDC | Total Patients, n | 2 | 3 | 13 | 12 | 2 | 32 |
| Visit # of referral, median (IQR) | 3.5 (1-6) | 1 (1-1) | 1 (1-3) | 1 (1-1) | 1 (1-1) | 1 (1-1) | |
| Months prior to death, median (IQR) | 11 (5-17) | 53 (17-67) | 14 (9-19) | 11 (7-16.5) | 8.5 (7-10) | 13 (8-19) | |
| Home care | |||||||
| Enrolled prior to MDC | Total patients, n (%) | 0 (0) | 0 (0) | 2 (8.3) | 8 (25.0) | 10 (55.6) | 20 (24.7) |
| Referred during MDC | Total Patients, n | 2 | 3 | 17 | 18 | 6 | 46 |
| Visit # of referral, median (IQR) | 6 (5-7) | 5 (3-11) | 2 (1-3) | 1 (1-2) | 1 (1-1) | 1 (1-3) | |
| Months prior to death, median (IQR) | 1.5 (1-2) | 7 (1-22) | 10 (8-17) | 10.5 (7-17) | 6 (2-8) | 9 (4-16) | |
| Oxygen | |||||||
| Initiated prior to MDC | Total patients, n (%) | 0 (0) | 0 (0) | 13 (54.2) | 19 (59.4) | 16 (88.9) | 48 (59.3) |
| Initiated during MDC | Total Patients, n | 3 | 2 | 5 | 6 | 1 | 17 |
| Visit # of initiation, median (IQR) | 4 (2-7) | 3 (2-4) | 3 (2-6) | 1 (1-2) | 2 (2-2) | 2 (1-4) | |
| Months prior to death, median (IQR) | 7 (2-23) | 18.5 (11-26) | 12 (6-23) | 10.5 (3-14) | 5 (5-5) | 11 (5-18) | |
| Patients on O2 at baseline with O2 titration during MDC | Total Patients, n | 0 | 0 | 13 | 18 | 12 | 43 |
| Visit # of titration, median (IQR) | — | — | 1 (1-1) | 1 (1-1) | 1 (1-1) | 1 (1-1) | |
| Months prior to death, median (IQR) | — | — | 15 (8-19) | 12 (6-22) | 3 (2-6.5) | 8 (3-18) | |
| Titration during MDC | Total Patients, n | 3 | 1 | 16 | 22 | 12 | 54 |
| Titrations per patient, median (IQR) | 1 (1-1) | 3 (3-3) | 3 (1-4) | 2 (1-3) | 2 (1-2) | 2(1-3) | |
| Any O2 intervention during MDC | Total patients, n (%) | 3 | 2 | 18 | 24 | 13 | 60 (74.1) |
| Interventions per patient, median (IQR) | 2 (2-2) | 2.5 (1-4) | 2.5 (1-4) | 2 (1.5-3) | 2 (1-2) | 2 (1-3) | |
| Opioid | |||||||
| Initiated prior to MDC | Total patients, n (%) | 0 (0) | 0 (0) | 1 (4.2) | 2 (6.3) | 6 (33.3) | 9 (11.1) |
| Initiated during MDC | Total patients, n (%) | 2 (50.0) | 1 (33.3) | 9 (37.5) | 14 (43.8) | 8 (44.4) | 34 (41.9) |
| Visit # of initiation, median (IQR) | 6.5 (5-8) | 10 (10-10) | 3 (2-5) | 2 (1-3) | 1 (1-1.5) | 2 (1-4) | |
| Months prior to death, median (IQR) | 1 (1-1) | 1(1-1) | 5 (4-10) | 3.5 (1-11) | 4 (2-7) | 4 (1-8) | |
| Patients on OP at baseline with dose adjustment during MDC | Total Patients, n | 0 | 0 | 1 | 1 | 6 | 8 |
| Visit # of dose adjustment, median (IQR) | — | — | 6 | 1 | 1 (1-1) | 1 (1-1) | |
| Months prior to death, median (IQR) | — | — | 2 | 10 | 2.5 (1-3) | 2.5 (1.5-6.5) | |
| Dose adjustment during MDC | Total Patients, n | 0 | 1 | 5 | 9 | 12 | 27 |
| Dose adjustments per patient, median (IQR) | — | 1 (1-1) | 1 (1-2) | 1 (1-2) | 1 (1-2) | 1 (1-2) | |
| Any OP intervention during MDC | Total Patients, n | 2 | 1 | 10 | 15 | 14 | 42 |
| Interventions per patient, median (IQR) | 1(1-1) | 1(1-1) | 1.5 (1-2) | 1 (1-3) | 2 (1-3) | 1.5 (1-2) | |
Abbreviations: IQR, interquartile range; MDC, multidisciplinary collaborative care; MRC, medical research council; O2, oxygen; OP, opioid; #, number.