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. 2023 Jan 19;23:15. doi: 10.1186/s12906-023-03839-7

Table 5.

Mortality rates (%) of T. spiralis adult worms exposed to different concentrations of C. rotundus 90% MeOH extract and its derived fractions by exposure times

Mortality rates (%) Drug dose μg/ml Exposure time (h)
Drugs 1 h 4 h 24 h 48 h 72 h
Albendazole 400 84 100 100 100 100
200 54 68 100 100 100
100 22 36 74 100 100
50 6 18 30 54 62
25 2 8 18 30 40
90% MeOH ext 500 22 26 52 76 100
250 14 20 34 62 90
125 6 8 22 32 54
50 0 2 10 22 32
25 0 0 6 18 18
EtOAc fr 500 30 40 68 86 100
250 18 28 46 72 100
125 10 12 34 48 66
50 6 8 16 26 36
25 0 4 6 16 20
Pet-ether fr 500 50 64 88 100 100
250 26 40 62 90 100
125 10 28 42 66 88
50 2 8 26 46 50
25 0 6 10 18 22
n-BuOH fr 500 62 76 100 100 100
250 42 60 90 100 100
125 22 36 58 100 100
50 8 10 28 44 56
25 4 6 14 26 30

Worm mortality % = (the number of dead worms / total number of worms) × 100%