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Graphical depiction of the results of the competitive displacements assays of hEGF, c(RGDyK), c(RGDfK), and both bispecific heterobivalent agents 1 and 2 on EGFR-positive A431 and integrin αvβ3-positive U87MG cells using [125I]I-EGF and [125I]I-echistatin as the competitors. Each experiment was performed thrice, each in triplicate.
