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. Author manuscript; available in PMC: 2023 Jan 19.
Published in final edited form as: Cell Rep. 2022 Dec 13;41(11):111835. doi: 10.1016/j.celrep.2022.111835

Figure 4. Interspecies recombination can promote antibiotic tolerance.

Figure 4.

Half-hour bacterial titers were taken after exposure to 10× MIC of penicillin for T4-derived in vitro-evolved strains (A and B), T4-derived first-round recombinant strains (C), T4-derived second-round recombinant strains (D), and T4-derived third-round recombinant strains (E). Bacterial growth is represented as a percentage of the bacterial CFU/mL taken at time = 0, prior to the addition of antibiotic. The prototypical multidrug-tolerant S. pneumoniae strain known as Tupelo was included as a reference for tolerance phenotype. Data are represented as mean CFU counts ± SD (n = 3).