Table 1. Kinetic Parameters of the Interaction of Mut FcγRIIIa with Commercially Available Full-Length Rituximab and Papain-Digested Rituximab-Fc at 25 °Ca.
kon (×104 M–1 s–1) | koff (×10–2 s–1) | KD (×10–6 M) | |
---|---|---|---|
rituximab | 4.45 ± 0.12 | 4.98 ± 0.09 | 1.12 ± 0.03 |
rituximab-Fc | 4.39 ± 0.23 | 7.21 ± 0.19 | 1.66 ± 0.08 |
Four independent measurements were carried out. The average values with standard errors are given.