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. 2022 May 23;62(2):262–269. doi: 10.1021/acs.biochem.1c00832

Table 1. Kinetic Parameters of the Interaction of Mut FcγRIIIa with Commercially Available Full-Length Rituximab and Papain-Digested Rituximab-Fc at 25 °Ca.

  kon (×104 M–1 s–1) koff (×10–2 s–1) KD (×10–6 M)
rituximab 4.45 ± 0.12 4.98 ± 0.09 1.12 ± 0.03
rituximab-Fc 4.39 ± 0.23 7.21 ± 0.19 1.66 ± 0.08
a

Four independent measurements were carried out. The average values with standard errors are given.