Table 3.
Dysregulation of circular RNAs and oxaliplatin resistance in colorectal cancer
|
CircRNAs
|
Expression1
|
Targets and pathways
|
Ref.
|
| circPTK2 | ↑ | miR-136-5P/YTHDF1 | [122] |
| (hsa_circ_0003221) | |||
| circ_0032833 | ↑ | miR-125-5p/MSI1 | [123] |
| hsa_circ_0079662 | ↑ | hsa-mir-324-5p/TNF-α/HOXA9 | [124] |
| circHIPK3 | ↑ | miR-637/STAT3/Bcl-2/Beclin1 | [125] |
| Circular CCDC66 | ↑ | PI3KK/p-DHX9 | [126] |
| hsa_circ_32883/ | ↑ | - | [127,128] |
| hsa_circ_0338 | ↑ |
1
Aberrant expression of circRNAs either up-regulated (↑) or down-regulated (↓) in CRC oxaliplatin resistance.
CircRNAs: Circular RNAs.