Table 1. Acute Toxicity Studies of Standards and Synthesized Compounds (6a–n).
number
of animals dead/tot number of animals tested,
dosage (mg/kg) |
||||
---|---|---|---|---|
compounds | 5 | 30 | 100 | 300 |
6a | 0/3 | 0/3 | 0/3 | 0/3 |
6b | 0/3 | 0/3 | 0/3 | 0/3 |
6c | 0/3 | 0/3 | 1/3 | 2/3 |
6d | 0/3 | 0/3 | 0/3 | 2/3 |
6e | 0/3 | 0/3 | 1/3 | 1/3 |
6f | 0/3 | 0/3 | 0/3 | 0/3 |
6g | 0/3 | 0/3 | 0/3 | 1/3 |
6h | 0/3 | 0/3 | 0/3 | 0/3 |
6i | 0/3 | 0/3 | 0/3 | 1/3 |
6j | 0/3 | 0/3 | 0/3 | 0/3 |
6k | 0/3 | 0/3 | 0/3 | 1/3 |
6l | 0/3 | 0/3 | 0/3 | 0/3 |
6m | 0/3 | 0/3 | 0/3 | 0/3 |
6n | 0/3 | 0/3 | 0/3 | 0/3 |
phenytoin | 0/3 | 0/3 | 0/3 | 0/3 |
phenobarbital | 0/3 | 0/3 | 0/3 | 0/3 |