. 2023 Jan 5;8(2):2520–2530. doi: 10.1021/acsomega.2c06967

Table 3. Antidepressant Activity of Most Active Anticonvulsant Compounds^a.

compound no.	basal means ± SEM	after treatment means ± SEM^a	% reduction
6f	379.4 ± 2.83	369.2 ± 3.08^ns	2.68
6h	374.8 ± 3.21	373.4 ± 3.85^ns	0.37
6j	370.6 ± 1.63	368.8 ± 2.63^ns	0.48
6l	378.6 ± 3.26	375.8 ± 3.65^ns	0.73
PEG-200	384.8 ± 2.67	379 ± 3.64^ns	1.50
diazepam	382.2 ± 4.70	74.6 ± 2.65**	80.4

n = 5; time = 5 min; the percent inhibition for each group was calculated by comparison with the control group. Dose = 100 mg/kg (p.o.); all values expressed as mean ± SEM (n = 5). *P ≤ 0.05, **P ≤ 0.01 as compared with control. Data were analyzed by one-way ANOVA followed by Dunnett’s test. 4 mg/kg (intraperitoneally).

Table 3. Antidepressant Activity of Most Active Anticonvulsant Compoundsa.

Table 3. Antidepressant Activity of Most Active Anticonvulsant Compounds^a.