TABLE 4.
Anti-MSP119 antibodies in Vietnam residents susceptible to and potentially protected against P. falciparum infection based on the presence or absence of P. falciparum parasitemia during the surveillance perioda
Isotype | Antibody prevalence (%)
|
Median antibody level (OD)
|
||||
---|---|---|---|---|---|---|
Susceptible (n = 47) | Protected (n = 33) | P (χ2) | Susceptible (n = 47) | Protected (n = 33) | P (U) | |
Total Ig | 95.7 | 97.0 | 1.000 | 0.667 (0.134, 1.775) | 0.418 (0.118, 1.084) | 0.636 |
IgG1 | 66.0 | 72.7 | 0.627 | 0.362 (0.037, 1.206) | 0.315 (0.061, 0.673) | 0.973 |
IgG2 | 6.4 | 9.1 | 0.687 | 0.014 (0.006, 0.024) | 0.012 (0.007, 0.029) | 0.476 |
IgG3 | 40.4 | 45.5 | 0.819 | 0.017 (0.004, 0.082) | 0.014 (0.008, 0.114) | 0.338 |
IgG4 | 0.0 | 0.0 | —b | −0.001 (−0.005, 0.008) | 0.000 (−0.003, 0.004) | 0.696 |
IgM | 34.0 | 42.4 | 0.488 | 0.312 (0.252, 0.536) | 0.389 (0.233, 0.580) | 0.513 |
See Table 2, footnotes a, b, and c. The threshold for significance is 0.0085 after an adjustment is made for the number of comparisons.
—, not compared due to negative value in both groups.